Monitoring Efek samping penggunaan antitrombotik pada pasien infark miokard akut di RS Swasta di Yogyakarta

Berikut Publikasi terbaru kami di Jurnal Farmasi Indonesia, ISSN 1412-1107, Vol 5 Nomor 1, Januari 2010

Dyah Aryani Perwitasari, Woro Supadmi, Kurniyati
Fakultas Farmasi, Universitas Ahmad Dahlan, Yogyakarta

Acute myocardial infarction (AMI) is one of coronary artery disease that has high rate of mortality and morbidity. The use of antithrombotic has ben recomended widely as the main therapy of AMI. The benefit from using aspirin in high-risk vascular disease patients comes at the cost of increased gastrointestinal complications. The complications include gastroduodenum ulcerations, dyspepsia, esophagitis and ulcerations in the stomach and duodenum. This research was aimed to know the monitoring of antithrombotics’side effects AMI patients in a private hospital of Yogyakarta from Januari to Desember 2007.
The research used descriptive method and the data was collected from patients’ medical records with AMI as primary diagnose
Result of research showed that antithombotics drugs which applied as therapy at AMI patient were antiplatelets, anticoagulants and thrombolytics. We identified the side effects monitoring such as; haemorrhage risk in 3,90% (2 patients), thrombocytopenia in 3,90% (2 patients) and renal function in 15,58% (12 patients). There were no patients with gastrointestinal disorder as antithrombotics’side effects. Intensive blood pressure monitoring was done for patient who get thrombolytic therapy (21 patients) that was equal to 26,92% from total patients.
Keywords : monitoring, side effect, antithrombotic, myocardium infarction, Yogyakarta


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